As a part of our ongoing efforts to develop tools with our colleagues in biology, we have designed and synthesized trifunctional linkers for expansion microscopy that overcome signal loss. This is a fruitful collaboration with Bo Huang and colleagues, and has enabled the highest resolution (5-nm) ExM to date!!
https://www.biorxiv.org/content/10.1101/687954v1
Also, this is our second preprint upload. I sense a trend starting…
Congrats to the team, especially the leaders Xiaoyu and Qi!